Next generation sequencing is evolving at a sensational pace and this has led to fantastic output and multiplexing of genomic regulation. It is now possible to study and analyze thousands of RNA Sequences for profiling applications. Small RNA sequencing facilitates the study of isoforms and expression patterns and plays a pivotal role in the discovery of many genetic diseases.

Milton, UK -- (SBWIRE) -- 06/17/2015 -- Small RNA sequencing has become accessible and feasible, and this opened up new opportunities for the discovery of disease causing DNA and identification of novel links that are suspected to be associated with human diseases. CD Genomics provide both basic and advanced bioinformatics analysis with a detailed report and final consultation. The company has a standard predefined procedure for accurate detection of small RNA.

Small RNA sequencing allows researchers to detect non-coding RNA, study variations using single-base resolution, and analyze miRNA without any information about the secondary structure. Small RNA sequencing can be effectively used to investigate the differential expression of small RNA in any given sample. This technology has made those studies possible which could not be imagined just a few years back and has made path breaking advancements in the disciplines of life sciences and clinical diagnostics. The advantages of availing small RNA sequencing services at CD Genomics include:

- Rapid turnaround time
- Accurate results
- Complete quality control
- High-throughput data
- Greater sensitivity

Small RNA sequencing facilitates an accurate measurement of transcripts and aids in the characterization of eukarytone transcriptomes. It is being used in the understanding of transcriptomics and also for quantification of each transcript along with mapping of transcribed areas. The technology is under progressive development and is currently employed for investigating complex transcriptomes since it allows unambiguous mapping and has a dynamic range with high levels of reproducibility for biological replicates. It needs less RNA sample and enables researchers to study transcriptomes in a quantitative manner. Small RNA sequencing is low-cost and generates unprecedented data for several species. It can determine expression patterns more accurately and gives increased depth and coverage. Due to all these advantages, it is fast replacing microarrays in several genome sequencing applications that relate to the dynamics of transcriptomes.

Researchers are now using small RNA sequencing for drug discovery, identification of cancer cells, the discovery of biomarkers and for guiding treatment decisions. CD Genomics proprietary GenSeqTM Technology provides accurate detection and quantification of small RNA sequencing services which include known and novel microRNA, piRNA and several other non-coding RNA, as well as the bioinformatics analysis of the RNA-Seq data.

About CD Genomics
CD Genomics is a leading biotechnology company based in New York offering fast and accurate genome sequencing services at competitive prices. The company provides comprehensive research solutions to educational institutions, government agencies and pharmaceutical companies. To avail their small RNA sequencing services, log on to cd-genomics.com.

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Thanks to the advancement of technology and medical science, scientists are able to study and analyze the immune system in a better way with the help of DNA sequencing and high-tech computation services. With the help of advanced immunosequencing process, we can uncover the risk of diseases and how they affect the immune system.

Milton, Cambridge -- (SBWIRE) -- 05/18/2015 -- The current advances in high-throughput sequencing has helped in the better analysis and probing of the immune system to study the various subtypes in the sequence. The technologically advanced machines can read innumerable B or T cell receptor sequences from a single sample at a time. The immune repertoire is the number of sub-types that exist in an organism's immune system.

The current interest in analyzing and researching how our immune system reacts to different germs, disease and whether it can detect them. The latest technology has changed the way we think about infectious diseases, immunity, and cancer. There is a reason why immune sequencing is big today and why scientists are showing a keen interest in it. The DNA sequencing which holds the immune repertoire is unlike other cell types which is why testing and immunosequencing can help in understanding how these cells react to the environment and the different diseases.

Immunosequencing At The Forefront As A Diagnostic Prototype For Infectious Diseases

Next-generation sequencing includes genome sequencing, resequencing, profiling are all important processes that can help in developing treatments that can increase immune repertoire and monitor the effects. Individual T and B cells are differentiated and identified through the unique receptors and they react differently with other cells of the immune system. With the help of the next-generation sequencing, the complexity of the T or B cell repertoire in a sequence can be analyzed for better understanding of the immune system. Immune Repertoire Sequencing Services can help in this endevour to fight chronic diseases.

There has been a lot of innovation in next-generation sequencing and the latest research includes analyzing and determining the development of the fetal adaptive immune system. Scientists are using next-generation sequencing to analyze and figure out the infectious risk of prematurely born infants. Sequencing also helps in identifying cancer cells and how the immune system protects the body from diseases. If a person's immune repertoire is low then they are more susceptible to diseases, which is why studies are undergoing to find ways to make the immune system recover faster. New strategies to develop specific cancer vaccines that can target multiple mutations are also being developed. Immune repertoire sequencing services offered by different organizations simply amplify & sequence the immune repertoire with next generation sequencing.

About CD Genomics
CD Genomics was established in 2004, and they aim to provide the research community with high-quality Next Generation Sequencing, high throughput microarray services. The ability to analyze and obtain data from several different sub types and cells at a time helps in determining a person's immune repertoire. With CD Genomics technological advancement and knowledge, the future seems compelling.

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CD Genomics has announced that it is now expanding its services to include human whole genome sequencing, molecular research, microarray analysis, construction of CDNA library and genotyping. With a view to transforming the way difficult to treat diseases are diagnosed and treated till date, the company is all set to take a plunge in path-breaking genetic research which will allow scientists to perform pioneering work in the field of life-science and preventive medicine.

Milton, Cambridge -- (SBWIRE) -- 04/15/2015 -- The company has over a decade of experience in providing scientists and researchers with high-quality CDNA libraries in a vector of choice. These libraries are compatible for EST sequencing, directional cloning and gene discovery. Stored as recombinant molecules at CD Genomics, these libraries can be reliably used for clone detection. Upon conclusion of the procedure, clients receive a comprehensive excel listing of all the genes sequenced along with glycerol stocks. The company has a flexible pricing that allows clients to pay only for the services they avail. From pharmaceutical companies and academic institutions to government agencies and research organizations, CD Genomics has been catering to a diversified client base for a decade now and has achieved notable progress in the field of molecular biology ever since its inception.

Construction of CDNA Library at CD Genomics will have the following advantages for researchers.

- DNA fragments that are isolated without cloning bias.
- High complexity and recombinant rate with low clone redundancy.
- Customer desired insert length.
- Strict quality control to confirm size and sequence identity of randomly sampled clones.
- Normalized CDNA library enriched for full length
- Eliminates the need for adaptor ligation for cloning
- Faster turnaround time for antibody screening

Full length-enriched construction of CDNA library is usually produced using modified template-switching approach. This method combines CDNA synthesis and amplification and results in representative CDNA population which is enriched with full-length sequences. On completion of CDNA synthesis, the double stranded CDNA is depleted using a Duplex-Specific Nuclease technique. This procedure allows for the precise elimination of particular transcripts without loss of average CDNA size. The uncut full length constructions of CDNA library enable the researcher to avoid restriction enzyme digestion during library construction. CD genomics strictly adheres to quality control measures to make sure that libraries are highly enriched for full-length CDNA clones.

Construction of CDNA Library will facilitate in the cloning of new genes, enable accurate analysis of gene expressions, precisely disclose SSR markers, assist in exploring the key genes that play a crucial role in preventing fatal diseases, make it possible for researchers to conduct transgenic research and in the construction of linkage maps.

About CD Genomics
CD Genomics is a leading biotechnology services company that specializes in DNA sequencing, aptamer development, Construction of CDNA Library, genotyping and whole human genome sequencing. Established in 2004, the company continues to expand upon its technology and technical know-how to deliver highly accurate and dependable services. To avail the services offered by CD Genomics, log on to cd-genomics.com.

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